Dissertations
2011
2011Doctorate
OKSİDATİF STRESLE AKTİVE EDİLEN TRPM2 KATYON KANALLARININ İNAKTİVASYONUNDA MELATONİNİN ETKİSİNİN PATCH-CLAMP SİSTEMİ İLE ARAŞTIRILMASI
Suleyman Demirel University, Sağlık Bilimleri Enstitüsü, Biyofizik Anabilim Dalı
Foreign Languages
B2 Upper Intermediate
B2 Upper IntermediateEnglish
Certificates, Courses and Trainings
2007
2007Patch-Clamp Method
Health&Medicine
RWTH - Aachen - Institute of Physiology - Prof. Dr. Lückhoff's Lab.
Research Areas
Medicine
Health Sciences
Fundamental Medical Sciences
Biophysics
Life Sciences
Biophysics
Neurobiophysics
Natural Sciences
Academic Titles / Tasks
2023 - Continues
2023 - ContinuesProfessor
Suleyman Demirel University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
2018 - 2023
2018 - 2023Associate Professor
Suleyman Demirel University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
2011 - 2018
2011 - 2018Assistant Professor
Suleyman Demirel University, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü
2009 - 2011
2009 - 2011Research Assistant
Suleyman Demirel University, Sağlık Bilimleri Enstitüsü, Biyofizik Anabilim Dalı
Published journal articles indexed by SCI, SSCI, and AHCI
2023
2023Downregulation of TRPM7, TRPM8, and TRPV1 channels modulate apoptotic parameters and neurodegenerative markers: Focus on neuronal differentiation and Parkinson's disease model
ÖZ A., ÇELİK Ö.
CELL BIOLOGY INTERNATIONAL
, vol.47, no.9, pp.1502-1518, 2023 (SCI-Expanded)
2023
2023Downregulation of TRPM8 channels induce cell death in human DBTRG glioblastoma cells
ÖZ A., ÇELİK Ö.
Indian Journal of Biochemistry and Biophysics
, vol.60, no.5, pp.385-392, 2023 (SCI-Expanded)
2023
2023LOW LEVEL LASER THERAPY REDUCES ANTICANCER POTENTIAL OF COLLOIDAL SILVER THROUGH TRPV1 CHANNELS SHORT TITLE: LLLT REDUCES ANTICANCER POTENTIAL OF COLLOIDAL SILVER
Övey İ. S., Güler Y., ÇELİK Ö.
Interciencia
, vol.48, no.5, pp.14-33, 2023 (SCI-Expanded)
2022
2022Evaluation of cognitive functions and EEG records in rats exposed to 2.45 GHz electromagnetic field
Yücel H., Olgaç Dündar N., Kumbul Doğuç D., Uğuz A. C., Çelik Ö., Aksoy F. T., et al.
International Journal of Radiation Research
, vol.20, no.4, pp.753-760, 2022 (SCI-Expanded)
2022
2022The effects of neuronal cell differentiation on TRPM7, TRPM8 and TRPV1 channels in the model of Parkinson's disease
ÖZ A., ÇELİK Ö.
NEUROLOGICAL RESEARCH
, vol.44, no.1, pp.24-37, 2022 (SCI-Expanded)
2019
2019Role of Selenium on MPP Neurotoxicity in SH-SY5Y Neuroblastoma Cells: Focus on TRPV1 Channels
ÖZ A., ÇELİK Ö., NAZIROĞLU M.
Turkish Journal Of Biochemistry-Türk Biyokimya Dergisi , vol.44, pp.65-68, 2019 (SCI-Expanded)
2018
2018Patch-Clamp Technique in Neuroscience
ÇELİK Ö.
ACTA PHYSIOLOGICA
, vol.225, pp.12, 2018 (SCI-Expanded)
2016
2016Oxidative stress of brain and liver is increased by Wi-Fi (2.45 GHz) exposure of rats during pregnancy and the development of newborns
ÇELİK Ö., Kahya M. C., NAZIROĞLU M.
JOURNAL OF CHEMICAL NEUROANATOMY
, vol.75, pp.134-139, 2016 (SCI-Expanded)
2016
2016Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure
ÖZ A., ÇELİK Ö.
MOLECULAR MEMBRANE BIOLOGY
, vol.33, pp.76-88, 2016 (SCI-Expanded)
2016
2016The effects of electromagnetic radiation (2450 MHz wireless devices) on the heart and blood tissue: role of melatonin
GÜMRAL N., SAYGIN M., AŞCI H., UGUZ A. C., ÇELİK Ö., DOGUC D. K., et al.
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
, vol.117, no.11, pp.665-671, 2016 (SCI-Expanded)
2015
2015Riboflavin and Vitamin E Increase Brain Calcium and Antioxidants, and Microsomal Calcium-ATP-ase Values in Rat Headache Models Induced by Glyceryl Trinitrate
BUTUN A., NAZIROĞLU M., DEMİRCİ S., ÇELİK Ö., UĞUZ A. C.
JOURNAL OF MEMBRANE BIOLOGY
, vol.248, no.2, pp.205-213, 2015 (SCI-Expanded)
2015
2015Protective Effects of Riboflavin and Selenium on Brain Microsomal Ca2+-ATPase and Oxidative Damage Caused by Glyceryl Trinitrate in a Rat Headache Model
NAZIROĞLU M., ÇELİK Ö., UĞUZ A. C., BÜTÜN A.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.164, no.1, pp.72-79, 2015 (SCI-Expanded)
2015
2015Melatonin attenuates apoptosis and mitochondrial depolarization levels in hypoxic conditions of SH-SY5Y neuronal cells induced by cobalt chloride (CoCl2)
UĞUZ A. C., ÖZ A., YILMAZ B., ALTUNBAŞ S., ÇELİK Ö.
TURKISH JOURNAL OF BIOLOGY
, vol.39, no.6, pp.896-903, 2015 (SCI-Expanded)
2014
2014Liver antioxidant stores protect the brain from electromagnetic radiation (900 and 1800 MHz)-induced oxidative stress in rats during pregnancy and the development of offspring
ÇETİN H., NAZIROĞLU M., ÇELİK Ö., YÜKSEL M., Pastaci N., ÖZKAYA M. O.
JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
, vol.27, no.18, pp.1915-1921, 2014 (SCI-Expanded)
2014
2014Melatonin and amfenac modulate calcium entry, apoptosis, and oxidative stress in ARPE-19 cell culture exposed to blue light irradiation (405 nm)
ARGUN M., TÖK L., Uguz A. C., ÇELİK Ö., TÖK Ö., NAZIROĞLU M.
EYE
, vol.28, no.6, pp.752-760, 2014 (SCI-Expanded)
2013
2013Wi-Fi (2.45 GHz)- and Mobile Phone (900 and 1800 MHz)-Induced Risks on Oxidative Stress and Elements in Kidney and Testis of Rats During Pregnancy and the Development of Offspring
ÖZORAK A., NAZIROĞLU M., ÇELİK Ö., YÜKSEL M., Ozcelik D., ÖZKAYA M. O., et al.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.156, pp.221-229, 2013 (SCI-Expanded)
2013
2013Basic Fibroblast Growth Factor Attenuates Bisphosphonate-Induced Oxidative Injury but Decreases Zinc and Copper Levels in Oral Epithelium of Rat
KOÇER G., NAZIROĞLU M., ÇELİK Ö., ÖNAL L., Ozcelik D., Kocer M., et al.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.153, pp.251-256, 2013 (SCI-Expanded)
2013
2013N-acetyl cysteine attenuates diazinon exposure-induced oxidative stress in rat testis
OKSAY T., NAZIROĞLU M., ERGÜN O., Dogan S., Ozatik O., Armagan A., et al.
ANDROLOGIA
, vol.45, no.3, pp.171-177, 2013 (SCI-Expanded)
2013
2013Modulation of wireless (2.45 GHz)-induced oxidative toxicity in laryngotracheal mucosa of rat by melatonin
AYNALİ G., NAZIROĞLU M., ÇELİK Ö., Dogan M., Yariktas M., YASAN H.
EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
, vol.270, no.5, pp.1695-1700, 2013 (SCI-Expanded)
2013
2013Capparis ovata Modulates Brain Oxidative Toxicity and Epileptic Seizures in Pentylentetrazol-Induced Epileptic Rats
NAZIROĞLU M., AKAY M. B., ÇELİK Ö., YILDIRIM M. I., BALCI E., YÜREKLİ V. A.
NEUROCHEMICAL RESEARCH
, vol.38, no.4, pp.780-788, 2013 (SCI-Expanded)
2012
2012Zinc Supplementation Attenuates Metallothionein and Oxidative Stress Changes in Kidney of Streptozotocin-Induced Diabetic Rats
Ozcelik D., NAZIROĞLU M., Tuncdemir M., ÇELİK Ö., Ozturk M., Flores-Arce M. F.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.150, pp.342-349, 2012 (SCI-Expanded)
2012
2012Melatonin modulates apoptosis and TRPM2 channels in transfected cells activated by oxidative stress
ÇELİK Ö., NAZIROĞLU M.
PHYSIOLOGY & BEHAVIOR
, vol.107, no.3, pp.458-465, 2012 (SCI-Expanded)
2012
2012Melatonin modulates wireless (2.45GHz)-induced oxidative injury through TRPM2 and voltage gated Ca 2+ channels in brain and dorsal root ganglion in rat
NAZIROĞLU M., ÇELİK Ö., Özgül C., Çiǧ B., Doǧan S., Bal R., et al.
Physiology and Behavior
, vol.105, no.3, pp.683-692, 2012 (SCI-Expanded)
2011
2011Selenium and l-Carnitine Reduce Oxidative Stress in the Heart of Rat Induced by 2.45-GHz Radiation from Wireless Devices
Turker Y., NAZIROĞLU M., GÜMRAL N., ÇELİK Ö., SAYGIN M., Comlekci S., et al.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.143, no.3, pp.1640-1650, 2011 (SCI-Expanded)
2011
2011Aminoethoxydiphenyl borate and flufenamic acid inhibit Ca2+ influx through TRPM2 channels in rat dorsal root ganglion neurons activated by ADP-ribose and rotenone
NAZIROĞLU M., ÖZGÜL C., ÇELİK Ö., Çiǧ B., SÖZBIR E.
Journal of Membrane Biology
, vol.241, no.2, pp.69-75, 2011 (SCI-Expanded)
2010
2010N-acetylcysteine modulates doxorubicin-induced oxidative stress and antioxidant vitamin concentrations in liver of rats
KOÇKAR M. C., NAZIROĞLU M., ÇELİK Ö., TOLA H. T., BAYRAM D., KOYU A.
CELL BIOCHEMISTRY AND FUNCTION
, vol.28, no.8, pp.673-677, 2010 (SCI-Expanded)
2010
2010Vitamins C and E treatment combined with exercise modulates oxidative stress markers in blood of patients with fibromyalgia: A controlled clinical pilot study
NAZIROĞLU M., AKKUŞ S., Soyupek F., YALMAN K., ÇELİK Ö., ERİŞ S., et al.
STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS
, vol.13, no.6, pp.498-505, 2010 (SCI-Expanded)
2010
2010Oral vitamin C and E combination modulates blood lipid peroxidation and antioxidant vitamin levels in maximal exercising basketball players
NAZIROĞLU M., Kilinc F., UGUZ A. C., ÇELİK Ö., Bal R., Butterworth P. J., et al.
CELL BIOCHEMISTRY AND FUNCTION
, vol.28, no.4, pp.300-305, 2010 (SCI-Expanded)
2009
2009Effects of Selenium and L-Carnitine on Oxidative Stress in Blood of Rat Induced by 2.45-GHz Radiation from Wireless Devices
GÜMRAL N., NAZIROĞLU M., Koyu A., Ongel K., ÇELİK Ö., SAYGIN M., et al.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.132, pp.153-163, 2009 (SCI-Expanded)
2009
2009Vitamin C and E combination modulates oxidative stress induced by X-ray in blood of smoker and nonsmoker radiology technicians
Kayan M., NAZIROĞLU M., Celik Ö., YALMAN K., Koeylue H.
CELL BIOCHEMISTRY AND FUNCTION
, vol.27, no.7, pp.424-429, 2009 (SCI-Expanded)
2009
2009Topiramate and Vitamin E Modulate the Electroencephalographic Records, Brain Microsomal and Blood Antioxidant Redox System in Pentylentetrazol-Induced Seizure of Rats
NAZIROĞLU M., Kutluhan S., UĞUZ A. C., Celik Ö., Bal R., Butterworth P. J.
JOURNAL OF MEMBRANE BIOLOGY
, vol.229, no.3, pp.131-140, 2009 (SCI-Expanded)
2009
2009Effects of Selenium and Topiramate on Lipid Peroxidation and Antioxidant Vitamin Levels in Blood of Pentylentetrazol-Induced Epileptic Rats
Kutluhan S., NAZIROĞLU M., Celik Ö., YILMAZ M.
BIOLOGICAL TRACE ELEMENT RESEARCH
, vol.129, pp.181-189, 2009 (SCI-Expanded)
2007
2007Venlafaxine modulates depression-induced oxidative stress in brain and medulla of rat
Eren İ., Naziroglu M., Demirdas A., Celik Ö., Uguz A. C., Altunbasak A., et al.
NEUROCHEMICAL RESEARCH
, vol.32, no.3, pp.497-505, 2007 (SCI-Expanded)
Articles Published in Other Journals
2020
2020Erlotinib and Melatonin Treatment Reduce Proliferation of the Neural Tumor Cells (SH-SY5Y) by Mediating TRPV1 Channel Function
ÖZKAL B., ÖVEY İ. S., ÇELİK Ö.
International Journal of Academic Medicine and Pharmacy , vol.2, no.2, pp.130-139, 2020 (Peer-Reviewed Journal)
2017
2017Effects of different doses of curcumin on apoptosis, mitochondrialoxidative stress and calcium influx in DBTRG glioblastoma cells
ÖZ A., ÇELİK Ö., ÖVEY İ. S.
Journal of Cellular Neuroscience and Oxidative Stress , vol.9, no.2, pp.617-629, 2017 (Scopus)
2017
2017Antioxidants: novel approach to ROS sensitive TRP channels gating manner.
ÖZ A., ÇELİK Ö., BEJERANO I., UĞUZ A. C.
Electronic Journal of Biology , vol.13, no.3, pp.243-246, 2017 (Peer-Reviewed Journal)
2010
2010Acamprosate Modulates Alcohol Induced Oxidative Stress In Alcoholic Patients
NAZIROĞLU M., EREN İ., ÇELİK Ö., ÇALIŞKAN A. M.
Cell Membranes and Free Radical Research , vol.2, no.2, pp.87-91, 2010 (Peer-Reviewed Journal)
Refereed Congress / Symposium Publications in Proceedings
2019
2019Have the TRP channels a role in MPP plus neurotoxicity?
Oz A., Celik Ö.
32nd Congress of the European-College-of-Neuropsychopharmacology (ECNP), Copenhagen, Denmark, 7 - 10 September 2019, vol.29
2018
2018LEPTİN VE β-GLUKANIN YARA İYİLEŞMESİ ÜZERİNE ETKİLERİNİNKARŞILAŞTIRILMASI
AK C., ÖZGÜNER M. F., GÜLTEKİN F., BÜYÜKBAYRAM H. İ., CANDAN İ. A., ÇELİK Ö.
1st International Health Sciences and Life Congress, 2 - 05 May 2018, pp.1097-1107
2015
2015Role of TRPC1 in CoCl2 induced neuronal cell death 6th Biennial Neuroscience Conference NEURIZONS2015 26 29th May 2015 Göttingen Germany Pages 6 7
ÇELİK Ö., ÖZ A., UĞUZ A. C., NAZIROĞLU M.
6th Biennial Neuroscience Conference (NEURIZONS2015), 26-29th May 2015, Göttingen, Germany. Pages 6-7., 26 - 29 May 2015
2015
2015Role of TRPC1 in CoCl2 induced neuronal cell death
ÇELİK Ö., ÖZ A., UĞUZ A. C., NAZIROĞLU M.
Neurizons 2015 – ‘Notes of an orchestrated brain’, Göttingen, Germany, 26 - 29 May 2015, pp.6-7
2015
2015SH SY5Y Hücrelerinde kobalt klorür ile indüklenmiş hipoksi modelinde melatoninin koruyucu rolü
UĞUZ A. C., ÖZ A., YILMAZ B., ALTUNBAŞ S., ÇELİK Ö.
13. Ulusal Sinir Bilim Kongresi, Konya, Turkey, 30 April - 03 May 2015
2015
2015SH SY5Y Hücrelerinde Kobalt Klorür ile İndüklenmiş Hipoksi Modelinde Melatoninin Koruyucu Rolü
UĞUZ A. C., ÖZ A., YILMAZ B., ALTUNBAŞ S., ÇELİK Ö.
13. Ulusal Sinirbilim Kongresi, Konya, Turkey, 30 April - 03 May 2015
2014
2014Sıçanlarda Bleomisin ile Oluşturulan Akciğer Fibrozisi Modelinde Nigella Sativa Yağının İnflamasyon, Fibrozis ve Antioksidan Enzimler Üzerine Etkisi
ÇAKIR M., KAYA S., BİRCAN S., ÇİRİŞ M., KUMBUL DOĞUÇ D., NAZIROĞLU M., et al.
TÜSAD 36. Ulusal Kongresi, İzmir, Turkey, 15 - 19 October 2014
2014
2014Protective effect of riboflavin and selenium on brain microsomal Ca2 ATP ase and oxidative damage caused by glyceryl trinitrate as a rat headache model
NAZIROĞLU M., ÇELİK Ö., UĞUZ A. C., BÜTÜN A.
5th International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signaling and TRP Channels, Isparta, Turkey, 9 - 12 September 2014, vol.6, pp.355-356
2012
2012N Acetyl Cystein Attenuates Chronic Diazinon Exposure Induced OxidativeStress in Rat Testis
OKSAY T., NAZIROĞLU M., ERGÜN O., DOĞAN S., ÖZATİK O., ARMAĞAN A., et al.
4th International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signaling and TRP Channels, 26 - 29 June 2012
2012
2012N Acetyl Cysteine Attenuates Chronic DiazinonExposure Induced Oxidative Stress in Rat Testis
OKSAY T., NAZIROĞLU M., ERGÜN O., DOĞAN S., ÖZATİK O., ÖZORAK A., et al.
4th International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signaling and TRP Channels, Isparta, Turkey, 26 - 29 June 2012, vol.4, pp.28
2009
2009Naziroglu, M., Uguz, A. C., Ozen, A., Çelik, O., Yalman, K., Demirci, S. (2009). Riboflavin and Selenium Modulates Brain antioxidant Redox System and Microsomal Ca2-atpase Activity in NitroglycerineInduced Migraine in Rats, European Journal of Pain. 13(1), 109
NAZIROĞLU M., UĞUZ A. C., Özen Bütün A., ÇELİK Ö., yalman k., DEMİRCİ S.
2009 European Federation of Chapters of the International Association for the Study of Pai, 1 - 02 September 2009, vol.13, pp.109
2010
2010N-Acetylcysteine Modulates Doxorubicin-Induced Liver Damage in Rats
KOÇKAR M. C., NAZIROĞLU M., ÇELİK Ö., TOLA H. T., BAYRAM D., KOYU A.
3rd International Congress on Cell Membranes and Oxidative Stress Focus on Calcium Signaling and TRP Channels, Isparta, Turkey, 22 - 27 June 2010, vol.2, pp.74
2008
20082 45 GHZ elektromanyetik radyasyonun oksidan antioksidan sistem üzerine etkisi ve L karnitin ile selenyumun koruyuculuğu
GÜMRAL N., NAZIROĞLU M., KOYU A., ÖNGEL K., ÇALIŞKAN S., SAYGIN M., et al.
Türk Fizyolojik Bilimler Derneği 34. Ulusal Fizyoloji Kongresi, Turkey, 6 - 10 October 2008, pp.134
2006
2006Depresyonda oluşturulan farelerin beyininde oksidatif stres üzeinde venlafaksinin etkileri
EREN İ., NAZIROĞLU M., DEMİRDAŞ A., ÇELİK Ö., UĞUZ A. C., ÖZMEN İ.
1. İyon kanalları ve oksidatif stres kongresi, Turkey, 14 - 16 September 2006
Activities in Scientific Journals
2018 - Continues
2018 - Continues