Doç. Dr. Nasıf Fatih KARAKUYU

1. A Comparison of the Use of In-situ Gels and Oral Sulfasalazine in the Treatment of Colitis

Elmas A., KARAKUYU N. F., Polat H. K., Selcuk E., İMECİ O. B., Camlica T., et al.

Journal of Pharmaceutical Innovation , cilt.21, sa.5, 2026 (SCI-Expanded, Scopus)

2. 17β-Estradiol accelerates corneal epithelial repair associated with anti-inflammatory and pro-regenerative molecular changes

USTA SOFU G., Karaca U., ERZURUMLU Y., Ozmen O., SAVRAN M., HASSEYİD N., et al.

Tissue and Cell , cilt.102, 2026 (SCI-Expanded, Scopus)

3. Antioxidant activity of Lavandula x intermedia and its healing effect against UVB-induced corneal damage in rats

Bulut S., Karakuyu N. F., Usta Sofu G., Tepebaşı M. Y., Özmen Ö., Yılmaz M. A., et al.

EXPERIMENTAL EYE RESEARCH , cilt.266, sa.110939, ss.110939, 2026 (SCI-Expanded, Scopus)

4. Phytochemical content, antioxidant and anti-inflammatory properties and wound healing effect of Chaiturus marrubiastrum: an in vitro and in vivo study

BULUT S., KARAKUYU N. F., Sarman E., Sidal A., KAHRAMAN A., Yilmaz M. A., et al.

Inflammopharmacology , cilt.34, sa.3, ss.1945-1957, 2026 (SCI-Expanded, Scopus)

5. Development of nimesulide-loaded pH-triggered ocular in situ gels; In vitro characterization, MTT assay and Drazie test.

Karakuyu N. F., Polat H. K., Unal S., Haydar M. K., Mokhtare B., Aykurt F., et al.

Drug development and industrial pharmacy , cilt.52, sa.5, ss.866-875, 2026 (SCI-Expanded, Scopus)

6. Development and characterization of olopatadine and verbascoside-loaded thermoresponsive in situ gels for ocular drug delivery: a factorial design approach for allergic conjunctivitis

Polat H. K., ÇOPUR T., PEZİK E., Turanlı Y., KARAKUYU N. F., Köngül E., et al.

Drug Development and Industrial Pharmacy , cilt.52, sa.8, ss.1561-1578, 2026 (SCI-Expanded, Scopus)

7. İlaç Yüklü Kontakt Lenslere Genel Bakış

Polat H. K., KARAKUYU N. F.

Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi , cilt.16, sa.3, ss.433-445, 2025 (TRDizin)

8. Thermosensitive in situ gel containing alpha-lipoic acid and rutin for the treatment of corneal neovascularization: formulation, characterization, and in vivo evaluation

Polat H. K., KARAKUYU N. F., ÜNAL S., Turanlı Y., PEZİK E., Sofu G. U., et al.

Journal of Drug Delivery Science and Technology , cilt.114, 2025 (SCI-Expanded, Scopus)

9. Herbal drug delivery for ocular treatments—an updated review

Polat H. K., Tunçel E., GÖZCÜ S., Turanlı Y., KARAKUYU N. F., ÜNAL S.

Experimental Eye Research , cilt.260, 2025 (SCI-Expanded, Scopus)

10. “Healing effect of homeopathic drug Theranekron in an alkaline-induced corneal injury model in rats”

Karakuyu N. F., Kaya M., Usta Sofu G., Sarman E.

EXPERIMENTAL EYE RESEARCH , cilt.258, ss.1-7, 2025 (SCI-Expanded, Scopus)

11. Fluvoxamine may reverse the decrease in filtering capacity that occurs in acute kidney injury by increasing IL-10 and ACE expressions and preserving AQ-2, AQ-4, CL-5, and ZO-1 expressions

KARAKUYU N. F., ÇAMLICA T., Asci H., Milletsever A., Ulusoy A., Gonuler F. M., et al.

Naunyn-Schmiedeberg's Archives of Pharmacology , cilt.398, sa.7, ss.9021-9029, 2025 (SCI-Expanded, Scopus)

12. Development of lacosamide-loaded in-situ gels through experimental design for evaluation of ocular irritation in vitro and in vivo

Çoban Ö., Pınar S. G., Polat H. K., Gedik G., Karakuyu N. F., Pezik E., et al.

Journal of Pharmaceutical Sciences , cilt.114, sa.2, ss.1342-1350, 2025 (SCI-Expanded, Scopus)

13. Effect of dapagliflozin on sepsis-induced kidney injury in a rat model: modulation of the NLRP3 pathway

İLHAN İ., KARAKUYU N. F., KARABACAK P., Milletsever A., Kolay O., Baysal G., et al.

Immunopharmacology and Immunotoxicology , cilt.47, sa.4, ss.533-540, 2025 (SCI-Expanded, Scopus)

14. “Investigation of the potential cellular changes induced by magnesium sulfate and salubrinal in a lipopolysaccharide-induced chorioamnionitis model”

AŞCI H., SAVRAN M., TEPEBAŞI M. Y., İLHAN İ., KARAKUYU N. F., İMECİ O. B., et al.

European Journal of Pharmacology , cilt.982, 2024 (SCI-Expanded, Scopus)

15. L-carnitine protects the lung from radiation-induced damage in rats via the AMPK/SIRT1/TGF-1ß pathway

KARAKUYU N. F., ÖZSEVEN A., AKIN S. E., ÇAMAŞ H. E., Özmen Ö., Cengiz Ç.

Naunyn-Schmiedeberg's Archives of Pharmacology , cilt.397, sa.10, ss.8043-8051, 2024 (SCI-Expanded, Scopus)

16. Formulation of hesperidin-loaded in situ gel for ocular drug delivery: a comprehensive study

GÖZCÜ S., Polat H. K., Gültekin Y., ÜNAL S., KARAKUYU N. F., Şafak E. K., et al.

Journal of the Science of Food and Agriculture , cilt.104, sa.10, ss.5846-5859, 2024 (SCI-Expanded, Scopus)

17. Beneficial Effects of Selenium on Kidney Injury via Nf-Kb and Aquaporin-1 Levels

Candan B., KARAKUYU N. F., GÜLLE K., Sarman E., ULUSOY KARATOPUK D.

Biological Trace Element Research , cilt.202, sa.8, ss.3653-3661, 2024 (SCI-Expanded, Scopus)

18. The Impact of Salubrinal in Preventing Fetal Brain Damage in a Model of Chorioamnionitis Induced by LPS

İçten P., Özkula S., Savran M., Gülle K., Erzurumlu Y., Karakuyu N. F., et al.

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi , cilt.31, sa.2, ss.159-165, 2024 (TRDizin)

19. Cannabidiol Mitigates Lipopolysaccharide-Induced Pancreatic Pathology: A Promising Therapeutic Strategy

Topsakal S., Ozmen O., KARAKUYU N. F., BEDİR M., SANCER O.

Cannabis and Cannabinoid Research , cilt.9, sa.3, ss.809-818, 2024 (SCI-Expanded, Scopus)

20. Harnessing silk fibroin microparticles for metformin delivery: A novel approach to treating corneal neovascularization

Polat H. K., AYTEKİN E., KARAKUYU N. F., Çaylı Y. A., ÇALAMAK S., Demirci N., et al.

Journal of Drug Delivery Science and Technology , cilt.96, 2024 (SCI-Expanded, Scopus)

21. OKÜLER İLAÇ TAŞIYICI SİSTEM OLARAK LİPİT BAZLI NANOPARTİKÜLLER

Polat H. K., AYTEKİN E., KARAKUYU N. F., Kurt N., Yazıksız Y.

Ankara Üniversitesi Eczacılık Fakültesi Dergisi , cilt.48, sa.2, ss.751-765, 2024 (Scopus, TRDizin)

22. Agomelatine ameliorates doxorubicin-induced cortical and hippocampal brain injury via inhibition of TNF-alpha/NF-kB pathway.

SAVRAN M., Asci S., GÜLLE K., ASLANKOÇ R., AŞCI H., KARAKUYU N. F., et al.

Toxicology mechanisms and methods , cilt.34, sa.4, ss.359-368, 2024 (SCI-Expanded, Scopus)

23. Evaluation of the Mixture "MagSelDex" For Neuroprotection Against Offspring Brain Injury in Endotoxin-Induced Chorioamnionitis: A Preliminary Study

aşcı h., SAVRAN M., GÜLBAG PINAR S., KARAKUYU N. F., İmeci O., Sevük M. A., et al.

Süleyman Demirel Üniversitesi Sağlık Bilimleri Dergisi , cilt.15, sa.1, ss.48-61, 2024 (TRDizin)

24. Investigation of neuroprotective and therapeutic effects of cannabidiol in an acute coronary syndrome model.

M D. U., D U., Karakuyu N. F., S A., O O., My T.

NEUROSCIENCE LETTERS , cilt.825, sa.825, ss.1-9, 2024 (SCI-Expanded, Scopus)

25. Gingerol Containing Polymeric Nanofibers: A Healing Touch for Accelerated Wound Recovery.

Polat H. K., Gözcü S., Ünal S., Paçacı T., Aytekin E., Karakuyu N. F., et al.

Drug development and industrial pharmacy , cilt.50, ss.706-719, 2024 (SCI-Expanded, Scopus)

26. Investigation of cardioprotective effect of lercanidipine on doxorubicin-induced cardiotoxicity

KARAKUYU N. F., SAVRAN M., Candan I. A., BÜYÜKBAYRAM H. İ., ERZURUMLU Y.

Naunyn-Schmiedeberg's Archives of Pharmacology , cilt.396, sa.12, ss.3635-3645, 2023 (SCI-Expanded, Scopus)

27. Irbesartan has a curative effect on lipopolysaccharide-induced cardiotoxicity by antioxidant and antiapoptotic pathways O irbesartan tem um efeito curativo na cardiotoxicidade induzida por lipopolissacarídeos por vias antioxidantes e antiapoptóticas

TEPEBAŞI M. Y., AŞCI H., COŞAN S., SEVÜK M. A., KARAKUYU N. F., Özmen Ö.

Revista Portuguesa de Cardiologia , cilt.42, sa.11, ss.895-903, 2023 (SCI-Expanded, Scopus)

28. Protective role of Nebivolol via AKT1/Hif-1α/eNOS signaling pathway: Nephrotoxicity caused by Methotrexate in a rat model.

Karakuyu N. F., Ertunc O., Bedir M., Doğan H. K., Taner R., Sevük M. A., et al.

Canadian journal of physiology and pharmacology , cilt.101, ss.393-399, 2023 (SCI-Expanded, Scopus)

29. Formulation Development of Dual Drug-Loaded Thermosensitive Ocular In Situ Gel Using Factorial Design

Polat H. K., Arslan A., ÜNAL S., HAYDAR M. K., AYTEKİN E., GÖZCÜ S., et al.

Journal of Pharmaceutical Innovation , cilt.18, sa.2, ss.768-788, 2023 (SCI-Expanded, Scopus)

30. PROTECTIVE ROLE OF SELENIUM ON THE HEART OF RATS EXPOSED ACRYLAMIDE

Karakuyu N. F., Aşcı H., Savran M., Gülle K.

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi , cilt.30, sa.1, ss.1-12, 2023 (TRDizin)

31. Nephroprotective effect of Astaxanthin against radiotherapy via TAS, TOS (biochemical), TNF-α, CASPASE-3 (immunohistochemical), SIRT-1, P53 (molecular) pathway in rats

Erkılınç G., Bedir M., Ayözger L. E. Ö., Doğan H. K., Karakuyu N. F.

Genel Tıp Dergisi , cilt.33, sa.33, ss.14-20, 2023 (Scopus, TRDizin)

32. Formulation development of Lornoxicam loaded heat triggered ocular in-situ gel using factorial design

Polat H. K., ÜNAL S., AYTEKİN E., KARAKUYU N. F., PEZİK E., HAYDAR M. K., et al.

Drug Development and Industrial Pharmacy , cilt.49, sa.9, ss.601-615, 2023 (SCI-Expanded, Scopus)

33. "Theranekron: A Novel Anti-inflammatory Candidate for Acetic Acid-Induced Colonic Inflammation in Rats"

SAVRAN M., AŞCI H., ERZURUMLU Y., ÖZMEN Ö., İLHAN İ., ŞİRİN M. C., et al.

MOLECULAR BIOLOGY REPORTS , cilt.49, sa.9, ss.8753-8760, 2022 (SCI-Expanded, Scopus)

34. Dexpanthenol Inhibits Inflammation and Apoptosis in LPS-Induced Acute Lung Injury by Reducing Increased VCAM-1 and Caspase-3 Expressions in Rats

Karakuyu N. F., Özmen Ö.

Kocatepe Veterinary Journal , cilt.15, sa.3, ss.303-310, 2022 (TRDizin)

Yayınlar & Eserler