Protective effects of aspirin and vitamin C against corn syrup consumption-induced cardiac damage through sirtuin-1 and HIF-1 alpha pathway

AŞCI, Halil; SAYGIN, Mustafa; YEŞİLOT, Sukriye; Topsakal, Senay; CANKARA, Fatma; Ozmen, Ozlem; Savran, Mehtap

doi:10.5152/anatoljcardiol.2015.6418

Protective effects of aspirin and vitamin C against corn syrup consumption-induced cardiac damage through sirtuin-1 and HIF-1 alpha pathway

Atıf İçin Kopyala

AŞCI H. , SAYGIN M. , YEŞİLOT S., Topsakal S., CANKARA F. N. , Ozmen O., ...Daha Fazla

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.16, sa.9, ss.648-654, 2016 (SCI İndekslerine Giren Dergi)

Cilt numarası: 16 Konu: 9
Basım Tarihi: 2016
Doi Numarası: 10.5152/anatoljcardiol.2015.6418
Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
Sayfa Sayıları: ss.648-654

Özet

Objective: The aim of this study was to investigate the protective effects of aspirin (AS) and vitamin C (VC) against cardiac damage induced by chronic corn syrup (CS) consumption via a mechanism involving sirtuin-1 (ST-1), hypoxia-inducible factor-1 alpha (HIF-1 alpha), and the caspase-3 pathway in rats.