Serum tumor necrosis factor-like weak inducer of apoptosis levels are elevated in schizophrenia.


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Kiliç F. , Işik Ü. , Usta A., Demirdaş A.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999), vol.43, pp.242-246, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43
  • Publication Date: 2021
  • Doi Number: 10.1590/1516-4446-2020-0950
  • Title of Journal : Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999)
  • Page Numbers: pp.242-246
  • Keywords: Neuroinflammation, serum level, schizophrenia, TWEAK, CYTOKINE ALTERATIONS, FACTOR SUPERFAMILY, PLASMA-LEVELS, TWEAK LEVELS, ASSOCIATION, SYMPTOMS, INFLAMMATION, INCREASES

Abstract

Objective: The purpose of this study was to assess serum Tumor necrosis factor-like weak inducer of apoptosis (TWEAK) concentrations to determine whether changes in patients with schizophrenia could have etiopathogenetic importance. Since very little research has addressed the connection between the inflammatory marker TWEAK and schizophrenia, we wanted to examine alterations of TWEAK and investigate the possible correlation between clinical symptomatology and serum concentrations.