Antimicrobial pyrazole dyes: synthesis, characterization, and absorption characteristics
RESEARCH ON CHEMICAL INTERMEDIATES, cilt.41, sa.4, ss.1985-1999, 2015 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 41 Sayı: 4
- Basım Tarihi: 2015
- Doi Numarası: 10.1007/s11164-013-1326-6
- Dergi Adı: RESEARCH ON CHEMICAL INTERMEDIATES
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1985-1999
- Anahtar Kelimeler: Pyrazole, Heterocyclic dye, Diazo coupling reaction, Spectroscopic property, Antimicrobial activity, DERIVATIVES
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Twenty-one novel pyrazole azo compounds were synthesized by coupling 3-amino-5-hydroxy-1H-pyrazole and 3-amino-1-phenyl-2-pyrazoline-5-one with diazonium salts derived from aniline, o, m, and p-nitroaniline, o and p-methoxyaniline, o, m, and p-chloroaniline, and o, m, and p-methylaniline. Spectroscopic data for these dyes, dissolved in six solvents, were measured. The effects of acid and base on the visible absorption spectra of the dyes are also reported. The structures of all the compounds were confirmed by Fourier-transform infrared spectroscopy, mass spectroscopy, ultraviolet and visible electronic absorption spectroscopy, nuclear magnetic resonance spectroscopy, and elemental analysis. In addition, the antimicrobial activity of the dyes against six pathogenic bacteria were examined in detail.