Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer

Bircan, Hacı; Gurbuz, Nilgün; Pataer, Apar; Caner, Ayse; Kahraman, Nermin; Bayraktar, Emine; Bayraktar, Recep; Erdogan, Mumin; Kabil, Nashwa; Ozpolat, Bulent

doi:10.1016/j.lungcan.2018.07.027

Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer

Atıf İçin Kopyala

Bircan H. A. , Gurbuz N. , Pataer A., Caner A., Kahraman N., Bayraktar E., ...Daha Fazla

LUNG CANCER, cilt.124, ss.31-39, 2018 (SCI İndekslerine Giren Dergi)

Cilt numarası: 124
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.lungcan.2018.07.027
Dergi Adı: LUNG CANCER
Sayfa Sayıları: ss.31-39

Özet

Objectives: Lung cancer is the leading cause of cancer related deaths in worldwide. Despite recent advances in treatment options, patient survival has not improved substantially due to lack of commonly expressed molecular targets and effective targeted therapeutics. Thus, better understanding of the biology of lung cancer and identification of novel therapeutic targets are urgently needed for development of highly effective molecularly targeted therapies.