Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer

Bircan, Hacı; Gurbuz, Nilgün; Pataer, Apar; Caner, Ayse; Kahraman, Nermin; Bayraktar, Emine; Bayraktar, Recep; Erdogan, Mumin; Kabil, Nashwa; Ozpolat, Bulent

doi:10.1016/j.lungcan.2018.07.027

Elongation factor-2 kinase (eEF-2K) expression is associated with poor patient survival and promotes proliferation, invasion and tumor growth of lung cancer

Bircan H. A. , Gurbuz N. , Pataer A., Caner A., Kahraman N., Bayraktar E., ...More

LUNG CANCER, vol.124, pp.31-39, 2018 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 124
Publication Date: 2018
Doi Number: 10.1016/j.lungcan.2018.07.027
Title of Journal : LUNG CANCER
Page Numbers: pp.31-39

Abstract

Objectives: Lung cancer is the leading cause of cancer related deaths in worldwide. Despite recent advances in treatment options, patient survival has not improved substantially due to lack of commonly expressed molecular targets and effective targeted therapeutics. Thus, better understanding of the biology of lung cancer and identification of novel therapeutic targets are urgently needed for development of highly effective molecularly targeted therapies.