Cholecalciferol (vitamin D3) prevents postoperative adhesion formation by inactivating the nuclear factor kappa B pathway: a randomized experimental study

Sahbaz A., Aynioglu O., Isik H., Gulle K., Ferah M. A., Sahbaz H. C.

JOURNAL OF SURGICAL RESEARCH, vol.198, no.1, pp.252-259, 2015 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 198 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1016/j.jss.2015.05.010
  • Journal Name: JOURNAL OF SURGICAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.252-259
  • Süleyman Demirel University Affiliated: No

Abstract

Background: Postoperative peritoneal adhesions are major complications of abdominopelvic surgeries. We aim to investigate the preventive and therapeutic effects of cholecalciferol (vitamin D3) supplementation on postoperative peritoneal adhesion (PPA) in a rat model.