Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia


ERDEMOĞLU E. , GÜNEY M., Giray S. G. , Take G., Mungan T.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, vol.145, no.2, pp.195-199, 2009 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 145 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1016/j.ejogrb.2009.04.034
  • Title of Journal : EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
  • Page Numbers: pp.195-199

Abstract

Objective: The effects of metformin on S6K1, which is a crucial effector of mTOR signaling, and on endometrium were studied in a mouse model of endometrial hyperplasia induced by unopposed estradiol or tamoxifen.