The Role of Inflammation in Preeclampsia

Sezik M.

21st European Congress of Perinatal Medicine, İstanbul, Türkiye, 10 - 13 Eylül 2008, ss.389-392, (Tam Metin Bildiri)

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Cilt numarası:
  • Basıldığı Şehir: İstanbul
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.389-392
  • Süleyman Demirel Üniversitesi Adresli: Evet

Özet

Preeclampsia is a syndrome with exaggeration of physiological systemic inflammation of pregnancy. Placenta seems to be the initial stimulus for activation of systemic inflammation. However, the presence of pre-pregnancy chronic inflammation is also a determining factor. This could explain why women with pre-existing hypertension, insulin resistance and increased body-mass index have increased risks of preeclampsia and vice versa. Investigations on limiting the inflammatory response by treating maternal infections or novel anti-inflammatory interventions to reduce the incidence or severity of preeclampsia are warranted.