Colistin alone or combined with sulbactam or carbapenem against A. baumannii in ventilator-associated pneumonia


Yilmaz G., Guven T., Guner R., KOÇAK TUFAN Z., Izdes S., Tasyaran M. A. , ...More

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, vol.9, no.5, pp.476-485, 2015 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 9 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.3855/jidc.6195
  • Journal Name: JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.476-485
  • Keywords: colistin, combined antibiotics, A. baumannii, ventilator-associated pneumonia, RESISTANT ACINETOBACTER-BAUMANNII, GRAM-NEGATIVE BACTERIA, COMBINATION THERAPY, INTRAVENOUS COLISTIN, AMPICILLIN-SULBACTAM, VS. COLISTIN, POLYMYXIN-B, IN-VITRO, INFECTIONS, EFFICACY

Abstract

Introduction: Colistin use has increased over the last ten years because of multidrug-resistant microorganisms. The aim of this study was to compare the clinical and microbiological efficacy of colistin alone or in combination with sulbactam or carbapenem in the treatment of ventilator-associated pneumonia (VAP) due to multidrug-resistant (MDR) and extremely drug-resistant (XDR) A. baumannii.