The role of immunohistochemical adrenomedullin and Bcl-2 expression in development of type-1 endometrial adenocarcinoma Adrenomedullin expression in endometrium


BOZKURT K. K. , YALÇIN Y., ERDEMOĞLU E. , TATAR B., ERDEMOĞLU E. , ÇERÇİ S. S. , ...Daha Fazla

PATHOLOGY RESEARCH AND PRACTICE, cilt.212, ss.450-455, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 212 Konu: 5
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1016/j.prp.2016.02.021
  • Dergi Adı: PATHOLOGY RESEARCH AND PRACTICE
  • Sayfa Sayıları: ss.450-455

Özet

Background: Adrenomedullin (AM) is a pluripotent peptide first discovered from human pheochromocytoma. AM expression has been shown in various cancer types including endometrium cancer. Bcl-2 is an antiapoptotic protein which might be regulated by AM in hypoxic conditions. The aim of the present study was to investigate the role of AM and Bcl-2 expressions in carcinogenesis of type-1 endometrium cancer.