Investigation of apoptotic effect of juglone on CCL-228-SW 480 colon cancer cell line

Bayram D., Özgöçmen M., Armağan İ., Sevimli M., Turel G. Y. , Şenol N.

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS, vol.15, no.1, pp.68-74, 2019 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.4103/jcrt.jcrt_880_17
  • Journal Name: JOURNAL OF CANCER RESEARCH AND THERAPEUTICS
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.68-74

Abstract

Background: Colon cancer is a major cause of morbidity and mortality in the world. Juglone is a natural compound which has been isolated from Juglans mandshurica Maxim, and it has various pharmacological effects such as antiviral, antibacterial, and anticancer. In our study, we aimed to investigate the effect of juglone on CCL-228-SW 480 colon carcinoma cell line in monolayer and spheroid culture medium.