Objective: Acne vulgaris occurs mostly during adolescence, a time when social and physical changes occur at the maximum level, and identity formation is a matter. In adolescence, when the perfect look is idealized, and in societies where physical attractiveness is important, acne can be a devastating disease. This study aims to evaluate the peer relationship, self-respect and anger level of 81 adolescents who presented to a dermatology outpatient clinic with acne in comparison with age-and sex-matched, healthy adolescents without any skin diseases. Methods: Acne severity was determined by GAGS (global acne grading system). Peer Relationship Scale, State-Trait Anxiety Inventory (STAI), State-Trait Anger Expression Inventory (STAXI) and Piers-Harris Children's Self-concept Scale was applied to 81 patient and 70 controls. Also patients completed Acne Quality of Life (AQL) Scale. Windows 18.0 SPSS statistical package was used for the data analysis. Results: There was no significant relationship between quality of life and gender and severity of acne. Significant correlations were detected between quality of life and trait anger and anger-in. There were no significant differences in terms of peer relationship, anger levels, anger style, Piers Harris total score and its subscale scores as intellectual and school status, behavior, conformity, popularity and social appreciation, anxiety, happiness and satisfaction between the acne and the control groups. However, the self esteem on physical appearance was significantly lower in acne group than in the control group. Discussion: In the view of above information, it was thought that it is necessary to recognize acne, not only as a cosmetic problem, but also a skin disease that impair mental health. This work suggests the need for social support and the importance of a multidisciplinary treatment approach in acne patients.