Economic damages which occur in the disaster are at enterprises time or later as physical, material and enterprises functions. Total, exportation of Denizli is USD 2.6 billion. Denizli is faced with serious risk of damage due to its big industrial enterprises that have industrial potential. There is a possibility of recurrence of fault lines, which destroyed magnificent earthquakes in ancient historical cities and had a big source of earthquakes. Because, as the region has active seismic fault lines and strains which are on more accumulate day by day. Moreover, the Majority of industrial enterprises in Denizli is prefabricated. Unfortunately, scientists say that these structures are dangerous. Denizli has experiences on management change in this period. City removes from the entire population which is above 500 thousands metropolitan city to management. So as city management, population exceeds one million and it has great structure compared to earlier. Correspondingly, the city gains more different dimension on disaster management. Factors in available locations of metropolitan management and disaster management do not match up with possibilities. In conclusion, fires, explosions which may take place in industrial enterprises in Denizli require the planning of emergency action and fire brigade placement tools, a new element of disaster. At work, aim to find available maps which can fire brigade responded at the optimum time with optimum placements using vehicles that occurred abo earthquake epicenters and fourth since 1900, disaster response locations available, the vital point of data operational research discipline approach via systems of industrial zones.