JOURNAL OF RESEARCH IN MEDICAL AND DENTAL SCIENCE, vol.10, no.8, pp.65-73, 2022 (ESCI)
Article / Article
JOURNAL OF RESEARCH IN MEDICAL AND DENTAL SCIENCE
Emerging Sources Citation Index (ESCI)
Lacosamide, Lipopolysaccharide, Kidney injury, Oxidative stress, Inflammation, ACUTE-RENAL-FAILURE, IN-VITRO MODEL, GLUTATHIONE-PEROXIDASE, BIOLOGICAL MARKER, SEPSIS, MALONDIALDEHYDE, DYSFUNCTION, MORTALITY, PRETREATMENT, DEFINITIONS
Süleyman Demirel University Affiliated:
Background: Sepsis is a well-known cause of multiple organ failure although its molecular mechanism is not fully defined. In this study, antioxidant, and anti-inflammatory effects of lacosamide (LCM) on the kidney tissue of rats with sepsis were investigated in the experimental LPS-induced sepsis model.