The relation of radiation-induced pulmonary fibrosis with stress and the efficiency of antioxidant treatment: An experimental study

KAYA, Vildan; YAZKAN, Rasih; YILDIRIM, Mustafa; Doguc, Duygu; Suren, Dinc; BOZKURT, Kemal; YÜKSEL, Ozlem; DEMİRPENÇE, Ozlem; Sen, Cenk; YALÇIN, Aysen

doi:10.12659/msm.890334

The relation of radiation-induced pulmonary fibrosis with stress and the efficiency of antioxidant treatment: An experimental study

KAYA V. , YAZKAN R. , YILDIRIM M., Doguc D. K. , Suren D., BOZKURT K. K. , ...More

MEDICAL SCIENCE MONITOR, vol.20, pp.290-296, 2014 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 20
Publication Date: 2014
Doi Number: 10.12659/msm.890334
Title of Journal : MEDICAL SCIENCE MONITOR
Page Numbers: pp.290-296

Abstract

Background: Radiation-Induced Lung Injury has 2 components: radiation pneumonitis and radiation fibrosis. The pulmonary fibrosis has no known efficient treatment. The purpose of this study was to study the relationship between the oxidant/antioxidant status and pulmonary fibrosis in rats having radiation induced pulmonary fibrosis and to study the antioxidant effects of pentoxifylline, vitamin E, and vitamin C in the treatment of pulmonary fibrosis.