Growth failure, tardive dyskinesia, megacolon development, and hepatic damage in neonatal rats following exposure to trimethobenzamide in utero


Erol A. Y. G. , Gokcimen A., Ozdemir O.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, vol.24, no.9, pp.1176-1180, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 9
  • Publication Date: 2011
  • Doi Number: 10.3109/14767058.2010.536867
  • Title of Journal : JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE
  • Page Numbers: pp.1176-1180

Abstract

Objective. Trimethobenzamide (TMB) has a pregnancy category C labeling. Tardive dyskinesia and gastrointestinal involvement in neonates were not described earlier. We aimed to investigate neurological, developmental, and hepatic effects of TMB.