Growth failure, tardive dyskinesia, megacolon development, and hepatic damage in neonatal rats following exposure to trimethobenzamide in utero

Erol A. Y. G. , Gokcimen A., Ozdemir O.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, vol.24, no.9, pp.1176-1180, 2011 (SCI-Expanded) identifier identifier identifier


Objective. Trimethobenzamide (TMB) has a pregnancy category C labeling. Tardive dyskinesia and gastrointestinal involvement in neonates were not described earlier. We aimed to investigate neurological, developmental, and hepatic effects of TMB.