In sepsis-associated cardiotoxicity, remifentanil reduces oxidative stress, inflammation, and apoptosis to maintain mitochondrial biogenesis by inhibiting NFkB and cas-3 immunoexpressions and enhancing SIRT1 upregulation.


Tepebaşi M. Y., Aşci H., Selçuk E., Uysal D., Bindal A., Yüksel D., ...Daha Fazla

Immunopharmacology and immunotoxicology, cilt.48, sa.1, ss.1-10, 2026 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 48 Sayı: 1
  • Basım Tarihi: 2026
  • Doi Numarası: 10.1080/08923973.2025.2585087
  • Dergi Adı: Immunopharmacology and immunotoxicology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Sayfa Sayıları: ss.1-10
  • Anahtar Kelimeler: apoptosis, cardiotoxicity, oxidative stress, remifentanil, Sepsis
  • Süleyman Demirel Üniversitesi Adresli: Evet