In sepsis-associated cardiotoxicity, remifentanil reduces oxidative stress, inflammation, and apoptosis to maintain mitochondrial biogenesis by inhibiting NFkB and cas-3 immunoexpressions and enhancing SIRT1 upregulation.

Tepebaşi M. Y., Aşci H., Selçuk E., Uysal D., Bindal A., Yüksel D., ...More

Immunopharmacology and immunotoxicology, vol.48, no.1, pp.1-10, 2026 (SCI-Expanded, Scopus)

  • Publication Type: Article / Article
  • Volume: 48 Issue: 1
  • Publication Date: 2026
  • Doi Number: 10.1080/08923973.2025.2585087
  • Journal Name: Immunopharmacology and immunotoxicology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, EMBASE, MEDLINE
  • Page Numbers: pp.1-10
  • Keywords: apoptosis, cardiotoxicity, oxidative stress, remifentanil, Sepsis
  • Süleyman Demirel University Affiliated: Yes