Unusual extramedullary hematopoiesis in a patient receiving granulocyte colony-stimulating factor

Dagdas S., Ozet G., Alanoglu G., Ayli M., Akoz A. G. , Erekul S.

ACTA HAEMATOLOGICA, vol.116, no.3, pp.198-202, 2006 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 116 Issue: 3
  • Publication Date: 2006
  • Doi Number: 10.1159/000094681
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.198-202


A 42-year-old woman was diagnosed with myelodysplastic syndrome with fibrosis that developed bilaterally, cervical lymphadenopathy and cutaneous infiltration by tri-lineage extramedullary hematopoiesis after granulocyte colony-stimulating factor therapy because of severe neutropenia. Hepatosplenomegaly was not observed during her follow-up. Extramedullary hematopoiesis disappeared after growth factor therapy was stopped. Although the neutropenia was alleviated by growth factor administration, the appearance of an unusual involvement of extramedullary hernatopoiesis should be kept in mind. Copyright (c) 2006 S. Karger AG, Basel.