miRNA-193b-5p Suppresses Pancreatic Cancer Cell Proliferation, Invasion, Epithelial Mesenchymal Transition, and Tumor Growth by Inhibiting eEF2K

---

Copy For Citation

GÜRBÜZ N., Kahraman N., Sonmez H. E., Mokhlis H. A., ASLAN KOŞAR P., Ozpolat B.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.22, no.14, pp.2607-2618, 2022 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 22 Issue: 14
• Publication Date: 2022
• Doi Number: 10.2174/1871520622666220117123213
• Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
• Page Numbers: pp.2607-2618
• Keywords: Pancreatic cancer, miRNA, miR-193b, EMT, eEF2K, proliferation, metastasis, PROMOTES PROLIFERATION, PROTEIN-KINASE, MICRORNAS, EXPRESSION, PROGRESSION, TUMORIGENESIS, METASTASIS, APOPTOSIS
• Süleyman Demirel University Affiliated: Yes

Abstract

Background: Pancreatic ductal adenocarcinoma ( PDAC) is the 4th leading cause of cancer deaths in the US due to the lack of effective targeted therapeutics and extremely poor prognosis.