miRNA-193b-5p Suppresses Pancreatic Cancer Cell Proliferation, Invasion, Epithelial Mesenchymal Transition, and Tumor Growth by Inhibiting eEF2K


GÜRBÜZ N., Kahraman N., Sonmez H. E., Mokhlis H. A., ASLAN KOŞAR P., Ozpolat B.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.22, no.14, pp.2607-2618, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 22 Issue: 14
  • Publication Date: 2022
  • Doi Number: 10.2174/1871520622666220117123213
  • Journal Name: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
  • Page Numbers: pp.2607-2618
  • Keywords: Pancreatic cancer, miRNA, miR-193b, EMT, eEF2K, proliferation, metastasis, PROMOTES PROLIFERATION, PROTEIN-KINASE, MICRORNAS, EXPRESSION, PROGRESSION, TUMORIGENESIS, METASTASIS, APOPTOSIS
  • Süleyman Demirel University Affiliated: Yes

Abstract

Background: Pancreatic ductal adenocarcinoma ( PDAC) is the 4th leading cause of cancer deaths in the US due to the lack of effective targeted therapeutics and extremely poor prognosis.