miRNA-193b-5p Suppresses Pancreatic Cancer Cell Proliferation, Invasion, Epithelial Mesenchymal Transition, and Tumor Growth by Inhibiting eEF2K

GÜRBÜZ, Nilgün; Kahraman, Nermin; Sonmez, Hafize; Mokhlis, Hamada; ASLAN KOŞAR, Pınar; Ozpolat, Bulent

doi:10.2174/1871520622666220117123213

miRNA-193b-5p Suppresses Pancreatic Cancer Cell Proliferation, Invasion, Epithelial Mesenchymal Transition, and Tumor Growth by Inhibiting eEF2K

GÜRBÜZ N., Kahraman N., Sonmez H. E., Mokhlis H. A., ASLAN KOŞAR P., Ozpolat B.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, cilt.22, sa.14, ss.2607-2618, 2022 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 22 Sayı: 14
Basım Tarihi: 2022
Doi Numarası: 10.2174/1871520622666220117123213
Dergi Adı: ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Biotechnology Research Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE
Sayfa Sayıları: ss.2607-2618
Anahtar Kelimeler: Pancreatic cancer, miRNA, miR-193b, EMT, eEF2K, proliferation, metastasis, PROMOTES PROLIFERATION, PROTEIN-KINASE, MICRORNAS, EXPRESSION, PROGRESSION, TUMORIGENESIS, METASTASIS, APOPTOSIS
Süleyman Demirel Üniversitesi Adresli: Evet

Özet

Background: Pancreatic ductal adenocarcinoma ( PDAC) is the 4th leading cause of cancer deaths in the US due to the lack of effective targeted therapeutics and extremely poor prognosis.