Quorum Sensing Inhibitor Activities of Celecoxib Derivatives in Pseudomonas aeruginosa


ULUSOY S. , ŞENKARDEŞ S., Coskun I., Bosgelmez-Tinaz G., Soulere L., Queneau Y., ...Daha Fazla

LETTERS IN DRUG DESIGN & DISCOVERY, cilt.14, ss.613-618, 2017 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 14 Konu: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.2174/1570180814666161121120719
  • Dergi Adı: LETTERS IN DRUG DESIGN & DISCOVERY
  • Sayfa Sayıları: ss.613-618

Özet

Background: A series of novel N-(substituted aryl/alkylcarbamothioyl)-4-[5-(4-methylphenyl)3-( trifluoromethyl)-1H-pyrazol-1-yl] benzene sulfonamides [SGK 318, 319, 320, 324, 327] and N-(3-substitutedaryl/ alkyl-4-oxo-1,3-thiazolidin-2-ylidene)-4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamides[SGK 328, 329, 330, 334, 337] were synthesized and tested for their quorum sensing inhibitor (QSI) capacity using quorum sensing inhibitor selector 1 (QSIS1) bioassay.