Bioactive borosilicate glasses are the most preferred and well-known glasses for orthopedic applications due to their excellent properties. However, some negative aspects of borosilicate glasses like low optical, structural, and electrical features restricted their use. Thus, to enhance the mentioned drawbacks, Ag2O with different ratios of x = 0, 2, 4, 6, 8, and 10 wt.% are added to the borosilicate glasses. The obtained results show that the Polaron radius (r(p)), Inter-nuclear distance (r(i)), and Field Strength will increase up to 4.8181 angstrom, 11.9570 angstrom, and 2.0246 x 10(16) cm(- 2). The transmittance, absorbance, and absorbance coefficient (alpha) are highly improved from BS-Ag0 to BS-Ag10. Furthermore, the values of constraint number (N-S) and cross-linking density (CD) show that the chosen samples' rigidity increase from 11.080 to 11.090 and 9.080 to 9.090. In addition, at the low energy region sudden peaks are recorded in C-eff curves for BS-Ag2, BS-Ag4, BS-Ag6, BS-Ag8, and BS-Ag10 at E = 25.51 KeV which is related to the K-edge absorption of the Ag element. From the obtained results it can be concluded that Ag2O is responsible for the enhancement of the radiation shielding, structural, optical, and electrical features of the bioactive borosilicate glasses.