Radiotherapy for Gastrointestinal Stromal Tumors
CHINESE MEDICAL JOURNAL, cilt.131, sa.2, ss.235-243, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 131 Sayı: 2
- Basım Tarihi: 2018
- Doi Numarası: 10.4103/0366-6999.222344
- Dergi Adı: CHINESE MEDICAL JOURNAL
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.235-243
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Objective: Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors of the gastrointestinal tract, which frequently cause intraabdominal metastases. The current standard of care is surgery for localized cases, and adjuvant imatinib is recommended for tumors with a high risk of recurrence. To date, radiotherapy has not been commonly accepted as a part of multimodality treatment approach other than palliation. However, recently published case reports and some small series suggest that radiotherapy is a valuable option for controlling locally progressive, drug-resistant disease. The aim of this review is to provide a viewpoint from a radiation oncologist concerning the management of GISTs, especially rectal GIST, and clarify the role and technical aspects of radiotherapy in the treatment approach.