Modulator role of infliximab and methotrexate through the transient receptor potential melastatin 2 (TRPM2) channel in neutrophils of patients with rheumatoid arthritis: a pilot study
ARCHIVES OF MEDICAL SCIENCE, cilt.15, sa.6, ss.1415-1424, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 15 Sayı: 6
- Basım Tarihi: 2019
- Doi Numarası: 10.5114/aoms.2018.79485
- Dergi Adı: ARCHIVES OF MEDICAL SCIENCE
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.1415-1424
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Introduction: Rheumatoid arthritis (RA) is a chronic, systemic, inflammatory disease causing symmetric polyarthritis. In this study, we aimed to investigate the effects of infliximab (INF) and methotrexate (MTX) on apoptosis, oxidative stress, and calcium signaling in the neutrophils of RA patients.