Avocados belong to the Plantae kingdom, the Lauraceae family, the order Laurales, the genus Persea, and the species P. americana. It is a plant-derived food which is implicated in various health-promoting and disease preventive effects. Therefore,it is considered a superfood. Avocado fruit pulp and peel, leaves and seeds are rich in both nutritive, such as vitamins, dietary fibers, and mineral and bioactive compounds, polyphenols, carotenoids, tocopherols and sterols. While carotenoids and tocopherols are mostly found in the fruit pulp, polyphenols are widely present in the fruit pulp and peel, seeds and leaves. Avocado fruit's seed (16%) and peel (11%) are consisted of 21-30% of the fruit as a solid waste except in some varieties. The rich bioactive compounds of avocado exhibited important biological activities in in vitro and in vivo studies, suggesting possible prevention against several diseases such as hypoglycemic, antihypertensive, antioxidant, obesity, hyperlipidemic, antimicrobial, antiprotozoal and antimycobacterial activity etc. Therefore, its effect on diseases has become a subject of interest in the literature. It was reported that the seed, peel and leaf of the fruit, especially from the avocado waste, have larvicidal, antifungal, antimicrobial, antioxidant, antiprotozoal, antidiabetic, antihypertensive, hypercholesterolemic and antimycobacterial activities such as stopping/slowing down many diseases. In this review, avocado tree; the bioactive components of the fruit pulp and peel, leaves and seeds and the effects of these components on health will be examined.