The Investigation of Gingival Iron Accumulation in Thalassemia Major Patients

Caliskan U., ÖZTÜRK TONGUÇ M., Ciris M., Balta N., KIRZIOĞLU F. Y., Caglayan G., ...More

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, vol.33, no.2, pp.98-102, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 2
  • Publication Date: 2011
  • Doi Number: 10.1097/mph.0b013e3182025058
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.98-102
  • Keywords: thalassemia, iron overload, gingiva, HEPATITIS-C PATIENTS, BETA-THALASSEMIA, LIVER IRON, OVERLOAD, FIBROSIS
  • Süleyman Demirel University Affiliated: Yes


Background: Thalassemia major (TM) is an autosomal-recessive genetic blood disorder. Regular blood transfusions to improve chronic anemia caused by ineffective erythropoiesis and hemolysis lead to iron overload in many organs in TM patients. The aim of this study was to investigate the periodontal status and the iron accumulation in gingival tissues of TM patients and assess whether iron deposition in gingival biopsies could be an alternative method for the diagnosis of body iron overload in TM patients.