Effects of atorvastatin on coronary flow reserve in patients with slow coronary flow

Caliskan M., Erdogan D., Gullu H., Topcu S., Ciftc O., Yildirir A., ...More

CLINICAL CARDIOLOGY, vol.30, no.9, pp.475-479, 2007 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 9
  • Publication Date: 2007
  • Doi Number: 10.1002/clc.20140
  • Journal Name: CLINICAL CARDIOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.475-479
  • Süleyman Demirel University Affiliated: No

Abstract

Background: Statins improve endothelial functioning in patients with coronary artery disease and hypercholesterolemia, while substantially little is known about induced changes in myocardial microcirculation. However, although previous studies have suggested that microvascular abnormalities and endothelial dysfunction is responsible for slow coronary flow (SCF), there is no study investigating possible effects of statins on coronary microvascular function in patients with SCF.