Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men


Perk H., Armagan A., Naziroglu M., Soyupek S., Hoscan M. B. , Suetcue R., ...Daha Fazla

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, cilt.33, ss.635-640, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 33 Konu: 6
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1111/j.1365-2710.2008.00962.x
  • Dergi Adı: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
  • Sayfa Sayıları: ss.635-640

Özet

Sildenafil citrate enhances the action of nitric oxide by preventing the hydrolysis of cGMP, and is widely used to treat erectile dysfunction. We investigated the effects of sildenafil citrate administration on lipid peroxidation and antioxidant redox enzymes in blood of healthy men.