Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Perk, H.; Armagan, A.; Naziroglu, M.; Soyupek, S.; Hoscan, M.; Suetcue, R.; Ozorak, A.; Delibas, N.

doi:10.1111/j.1365-2710.2008.00962.x

Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Perk H., Armagan A., Naziroglu M., Soyupek S., Hoscan M. B., Suetcue R., ...Daha Fazla

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, cilt.33, sa.6, ss.635-640, 2008 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 33 Sayı: 6
Basım Tarihi: 2008
Doi Numarası: 10.1111/j.1365-2710.2008.00962.x
Dergi Adı: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.635-640
Süleyman Demirel Üniversitesi Adresli: Evet

Özet

Sildenafil citrate enhances the action of nitric oxide by preventing the hydrolysis of cGMP, and is widely used to treat erectile dysfunction. We investigated the effects of sildenafil citrate administration on lipid peroxidation and antioxidant redox enzymes in blood of healthy men.