Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Perk, H.; Armagan, A.; Naziroglu, M.; Soyupek, S.; Hoscan, M.; Suetcue, R.; Ozorak, A.; Delibas, N.

doi:10.1111/j.1365-2710.2008.00962.x

Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Copy For Citation

Perk H., Armagan A., Naziroglu M., Soyupek S., Hoscan M. B. , Suetcue R., ...More

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.33, no.6, pp.635-640, 2008 (SCI-Expanded)

Publication Type: Article / Article
Volume: 33 Issue: 6
Publication Date: 2008
Doi Number: 10.1111/j.1365-2710.2008.00962.x
Journal Name: JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.635-640
Süleyman Demirel University Affiliated: Yes

Abstract

Sildenafil citrate enhances the action of nitric oxide by preventing the hydrolysis of cGMP, and is widely used to treat erectile dysfunction. We investigated the effects of sildenafil citrate administration on lipid peroxidation and antioxidant redox enzymes in blood of healthy men.