Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Perk H., Armagan A., Naziroglu M., Soyupek S., Hoscan M. B. , Suetcue R., ...More

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.33, no.6, pp.635-640, 2008 (SCI-Expanded) identifier identifier identifier


Sildenafil citrate enhances the action of nitric oxide by preventing the hydrolysis of cGMP, and is widely used to treat erectile dysfunction. We investigated the effects of sildenafil citrate administration on lipid peroxidation and antioxidant redox enzymes in blood of healthy men.