Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Perk, H.; Armagan, A.; Naziroglu, M.; Soyupek, S.; Hoscan, M.; Suetcue, R.; Ozorak, A.; Delibas, N.

doi:10.1111/j.1365-2710.2008.00962.x

Sildenafil citrate as a phosphodiesterase inhibitor has an antioxidant effect in the blood of men

Perk H., Armagan A., Naziroglu M., Soyupek S., Hoscan M. B. , Suetcue R., ...More

JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, vol.33, no.6, pp.635-640, 2008 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 33 Issue: 6
Publication Date: 2008
Doi Number: 10.1111/j.1365-2710.2008.00962.x
Title of Journal : JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS
Page Numbers: pp.635-640

Abstract

Sildenafil citrate enhances the action of nitric oxide by preventing the hydrolysis of cGMP, and is widely used to treat erectile dysfunction. We investigated the effects of sildenafil citrate administration on lipid peroxidation and antioxidant redox enzymes in blood of healthy men.