Serum Claudin-5, but not Zonulin, May Be Associated with Obsessive-Compulsive Disorder.

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Kılıç F., Işık Ü., Kumbul Doğuç D.

Psychiatria Danubina, vol.34, no.2, pp.273-278, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 2
  • Publication Date: 2022
  • Doi Number: 10.24869/psyd.2022.273
  • Journal Name: Psychiatria Danubina
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus, EMBASE, Psycinfo, Social services abstracts
  • Page Numbers: pp.273-278
  • Keywords: blood-brain barrier, claudin-5, intestinal permeability, zonulin, obsessive-compulsive disorder, BARRIER, SCALE
  • Süleyman Demirel University Affiliated: Yes


Background: The aim of this research was to assess serum zonulin and claudin-5 concentrations to show whether or not their eventual changes in patients with obsessive-compulsive disorder (OCD) could have etiopathogenetic importance. There was no research in the literature assessing serum zonulin and claudin-5 levels in OCD to the best of our understanding.