Aim: To assess the relationship between tonsillectomy indications and neutrophil/lymphocyte ratio (NLR) and trombocyte/lymphocyte ratio (TLR). Material and Method: In our retrospective study, conducted between 2012-2016, the study group consisted of 200 boys whose chief complaint was frequent tonsillitis and who therefore had a tonsillectomy due to chronic tonsillitis. The control group consisted of 100 healthy boys who had been circumcised in the Urology or Pediatric Surgery Departments. The files of patients and controls were retrospectively evaluated. Results: There was no statisticially significant difference between the study group and the control group in terms of age, leukocyte, trombocyte, neutrophil count, or RDW value. In the study group, NLR and TLR (p=0.001 and p=0.011, respectively) were higher than in the control group and these findings are statistically significant. Discussion: NLO was higher in the study group than the control group. We also observed that it was the decrease in the lymphocyte count that caused the higher NLR, unlike the situation with oncologic patients whose higher NLR values are due to increased neutrophil counts. Also, TLO was higher in the study group than the control group, due not to higher trombocyte counts but instead to lower lymphocyte counts. In conclusion we believe that while an NLO ratio of 1.48 can not serve as a definitive indication for tonsillectomy, it can be used to support already-established indications.