Investigation of immunohistochemical ER alpha, ER beta and ER beta cx expressions in normal and neoplastic breast tissues


BOZKURT K. K., KAPUCUOĞLU N.

PATHOLOGY RESEARCH AND PRACTICE, vol.208, no.3, pp.133-139, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 208 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.prp.2011.12.015
  • Journal Name: PATHOLOGY RESEARCH AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.133-139
  • Süleyman Demirel University Affiliated: Yes

Abstract

Estrogen receptor alpha (ER alpha) is a well-established prognostic marker in breast cancer. The role of estrogen receptor beta (ER beta) in breast cancers is still under investigation. We aimed to investigate the clinicopathological significance and immunohistochemical expression patterns of ER alpha, total ER beta (ER beta) and its spliced variant ER beta cx in normal breast, ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC).