Investigation of immunohistochemical ER alpha, ER beta and ER beta cx expressions in normal and neoplastic breast tissues


BOZKURT K. K. , KAPUCUOĞLU N.

PATHOLOGY RESEARCH AND PRACTICE, vol.208, no.3, pp.133-139, 2012 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 208 Issue: 3
  • Publication Date: 2012
  • Doi Number: 10.1016/j.prp.2011.12.015
  • Title of Journal : PATHOLOGY RESEARCH AND PRACTICE
  • Page Numbers: pp.133-139

Abstract

Estrogen receptor alpha (ER alpha) is a well-established prognostic marker in breast cancer. The role of estrogen receptor beta (ER beta) in breast cancers is still under investigation. We aimed to investigate the clinicopathological significance and immunohistochemical expression patterns of ER alpha, total ER beta (ER beta) and its spliced variant ER beta cx in normal breast, ductal carcinoma in situ (DCIS) and invasive ductal carcinoma (IDC).