Quorum sensing and virulence of Pseudomonas aeruginosa during urinary tract infections


Senturk S., ULUSOY S., Bosgelmez-Tinaz G., Yagci A.

JOURNAL OF INFECTION IN DEVELOPING COUNTRIES, vol.6, no.6, pp.501-507, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 6
  • Publication Date: 2012
  • Journal Name: JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.501-507
  • Keywords: P. aeruginosa, quorum sensing, virulence factors, CHROMOBACTERIUM-VIOLACEUM, EXPRESSION, PNEUMONIA, MODEL
  • Süleyman Demirel University Affiliated: Yes

Abstract

Introduction: In the opportunistic pathogen Pseudomonas aeruginosa, the production of several virulence factors depends on quorum sensing (QS) involving N-acylhomoserine lactone signal molecules. In vitro studies have suggested that the QS system is crucial in the pathogenesis of P. aeruginosa. However, it is unclear whether QS systems of P. aeruginosa play the same role during infections.