The role of High Mobility Group Box 1 (HMGB1) in colorectal cancer


Suren D., Yildirim M., Demirpence O., KAYA V. , Alikanoglu A. S. , Bulbuller N., ...Daha Fazla

MEDICAL SCIENCE MONITOR, cilt.20, ss.530-537, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 20
  • Basım Tarihi: 2014
  • Doi Numarası: 10.12659/msm.890531
  • Dergi Adı: MEDICAL SCIENCE MONITOR
  • Sayfa Sayıları: ss.530-537

Özet

Background: HMGB1, the most important member of the high mobility group box protein family, is a nuclear protein with different functions in the cell; it has a role in cancer progression, angiogenesis, invasion, and metastasis development. We studied the expression of HMGB1 and whether it is a prognostic factor in colorectal carcinoma.