The role of oxidants and antioxidants in psoriasis.


Yildirim M. , Inaloz H., Baysal V., Delibas N.

Journal of the European Academy of Dermatology and Venereology : JEADV, vol.17, no.1, pp.34-6, 2003 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 1
  • Publication Date: 2003
  • Doi Number: 10.1046/j.1468-3083.2003.00641.x
  • Title of Journal : Journal of the European Academy of Dermatology and Venereology : JEADV
  • Page Numbers: pp.34-6
  • Keywords: antioxidants, oxidants, psoriasis, reactive oxygen species, SUPEROXIDE GENERATION, FREE-RADICALS, FIBROBLASTS

Abstract

Background Psoriasis vulgaris is a chronic inflammatory skin disease characterized by well-demarcated erythema and scaly plaques. The pathogenesis of psoriasis still remains unclear. An increased reactive oxygen species (ROS) and insufficient antioxidant activity have been determined in psoriatic lesions.