This study aims to evaluate the current position of the interdependence theory which existed in the literature of international relations for over thirty years. The study focuses particularly on the theory of interdependence as formulated by Keohane and Nye and its development. Keohane and Nye's pluralist understanding of international relations got into transformation and drove through several stages with the international system itself. After its early years, the pattern of interdependence has followed up a line of evolution from complex interdependence to globalism. The study, after evaluating these stages, discusses the term of interdependence within the context of USA-Japan relations and the linkage of USA with international leadership, and arrives at the conclusion that the terms of interdependence and globalization are not equivalent, but complementary.