Cyclooxygenase-2 expression in primary and recurrent pterygium

KARAHAN N., Baspinar S., Ciris M., BAYDAR Ç. L., Kapucuoglu N.

INDIAN JOURNAL OF OPHTHALMOLOGY, vol.56, no.4, pp.279-283, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.4103/0301-4738.39663
  • Journal Name: INDIAN JOURNAL OF OPHTHALMOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.279-283
  • Süleyman Demirel University Affiliated: Yes

Abstract

Background: Pterygia are common, benign, fibrovascular, and infiltrative processes of the corneo-conjunctival junction of unknown pathogenesis. Cyclooxygenase-2 (COX-2) mediates the rate-limiting step in arachidonic acid metabolism. Extensive evidence indicates that the COX-2 prostanoid pathway is involved in inflammation. The aim of the study was to document the immunohistochemical expression of COX-2 in primary and recurrent pterygia.