NEUROCHEMICAL RESEARCH, vol.32, no.1, pp.19-25, 2007 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
morphine, fatty, acids, brain, lipid peroxidation, spinal cord, glutathione, VITAMIN-E, LIVER-TISSUES, CANCER PAIN, DRUGS, RATS, NEUROTOXICITY, SELENIUM, RELEASE, PRODUCT, DAMAGE
Süleyman Demirel University Affiliated:
It is well known that oxidative stress damages bimolecules such as DNA and lipids. No study is available on the morphine-induced oxidative damage and fatty acids changes in brain and spinal tissues. The aim of this work was to determine the effects of morphine on the concentrations and compositions of fatty acid in spinal cord segments and brain tissues in rabbits as well as lipid peroxidation (LP) and glutathione (GSH) levels in cortex brain.