We estimate Lg wave attenuation using local and regional seismic phases in the Isparta Angle and the Anatolian Plateau (Turkey). The Isparta Angle (IA) is a tectonically active zone forming the boundary between the African Plate and the Anatolian Plateau, and is currently undergoing N-S extensional deformation. The Anatolian Plateau contains many intra-continental faults including the North Anatolian Fault Zone and the East Anatolian Fault Zone as well as the Menderes Massif. A large waveform data set was compiled from a variety of local and regional seismic networks including 121 digital seismic stations (broad-band and short period) between 1999 and 2008 spanning the IA, the Anatolian Plateau and Azerbaijan. The data set was used to determine the nature of Lg wave propagation and characterize the nature of seismic attenuation within the crust of these regions. Lg waveforms were used to calculate the frequency-dependent Lg-Q(o) and Lg-eta. A wide range of Lg-Q(o) values was obtained between similar to 52 +/- 6 and 524 +/- 227. Low Lg-Q(o) values (similar to 90-155) are calculated towards the north of IA, Iskenderun Gulf and its vicinity, Bingol-Karliova, Izmit and its vicinity. Lg-Q(o) values are especially low (<90) along the Menderes Massif and the Aksehir-Simav Fault Zones. This may be due to intrinsic attenuation of Lg associated with the partially molten crust and young volcanism. The high Lg-Q(o) values (similar to 350) are probably caused by the crust not being subject to large amounts of extensional deformation like the Antalya Gulf and apparently being thick enough to support Lg propagation. Relatively higher values along the border of this subduction zone and plate boundary might be related to the Taurus Mountain belts and Bitlis-Zagros Suture Zone. The lateral frequency dependency Lg-eta is also consistent with high tectonic activity in this region.