Multi-organ injuries caused by lipopolysaccharide-induced periodontal inflammation in rats: role of melatonin


Gulle K., Akpolat M., Kurcer Z., Cengiz M. I. , Baba F., Acikgoz S.

JOURNAL OF PERIODONTAL RESEARCH, cilt.49, ss.736-741, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 49 Konu: 6
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1111/jre.12156
  • Dergi Adı: JOURNAL OF PERIODONTAL RESEARCH
  • Sayfa Sayıları: ss.736-741

Özet

Background and ObjectivePeriodontitis, a chronic inflammatory disease caused by oral bacterial infection, is considered to be a risk factor for systemic diseases including diabetes mellitus, bacterial pneumonia, hyperlipidemia and atherosclerosis. The aim of this study was to evaluate the effectiveness of melatonin against periodontal inflammation-induced multiple organ injury in rats.