Multi-organ injuries caused by lipopolysaccharide-induced periodontal inflammation in rats: role of melatonin

Gulle K., Akpolat M., Kurcer Z., Cengiz M. I., Baba F., Acikgoz S.

JOURNAL OF PERIODONTAL RESEARCH, vol.49, no.6, pp.736-741, 2014 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 6
  • Publication Date: 2014
  • Doi Number: 10.1111/jre.12156
  • Journal Name: JOURNAL OF PERIODONTAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.736-741
  • Süleyman Demirel University Affiliated: No

Abstract

Background and ObjectivePeriodontitis, a chronic inflammatory disease caused by oral bacterial infection, is considered to be a risk factor for systemic diseases including diabetes mellitus, bacterial pneumonia, hyperlipidemia and atherosclerosis. The aim of this study was to evaluate the effectiveness of melatonin against periodontal inflammation-induced multiple organ injury in rats.