The effect of fixed-dose combination of valsartan and amlodipine on nighttime blood pressure in patients with non-dipper hypertension
TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, cilt.44, sa.5, ss.404-413, 2016 (ESCI, Scopus, TRDizin)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 44 Sayı: 5
- Basım Tarihi: 2016
- Doi Numarası: 10.5543/tkda.2015.98250
- Dergi Adı: TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
- Sayfa Sayıları: ss.404-413
- Anahtar Kelimeler: Amlodipine, ambulatory blood pressure, non-dipper, fixed dose combination, valsartan, DOUBLE-BLIND, CARDIOVASCULAR EVENTS, PARALLEL-GROUP, MONOTHERAPY, EFFICACY, THERAPY, RISK, TOLERABILITY, OPTIMIZATION, PREVENTION
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Objective: Failure to decrease blood pressure (BP) during the night is associated with higher cardiovascular (CV) morbidity and mortality. There is strong evidence that fixed-dose combinations (FDCs) of antihypertensive agents are associated with significant improvement and non-significant adverse effects. The aim of the present study was to evaluate whether FDC affected nocturnal BP favorably in patients with uncontrolled, non-dipper hypertension (HT).