Effect of Curcumin on Systemic T Helper 17 Cell Response; Gingival Expressions of Interleukin-17 and Retinoic Acid Receptor-Related Orphan Receptor gamma t; and Alveolar Bone Loss in Experimental Periodontitis
JOURNAL OF PERIODONTOLOGY, cilt.87, sa.11, 2016 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 87 Sayı: 11
- Basım Tarihi: 2016
- Doi Numarası: 10.1902/jop.2016.150722
- Dergi Adı: JOURNAL OF PERIODONTOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Anahtar Kelimeler: Alveolar bone loss, curcumin, interleukin-17, interleukin-23, periodontitis, Th17, TH17 CELLS, ANTIINFLAMMATORY AGENT, IL-17, AUTOIMMUNE, DISEASE, LIGAND, SITES, BETA, DIFFERENTIATION, PROGRESSION
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Background: Curcumin has anti-inflammatory and antioxidant effects and is reported to have many biologic activities. The current study examines effect of curcumin on: 1) systemic T helper 17 (Th17) cell response; 2) gingival expressions of interleukin (IL)-17 and retinoic acid receptor-related orphan receptor (ROR) gamma t; and 3) alveolar bone loss (ABL) in experimental periodontitis.