The effects of n-3 polyunsaturated fatty acids by gavage on some metabolic enzymes of rat liver
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, vol.71, no.2, pp.131-135, 2004 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 71 Issue: 2
- Publication Date: 2004
- Doi Number: 10.1016/j.plefa.2004.03.002
- Journal Name: PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.131-135
- Süleyman Demirel University Affiliated: No
Abstract
In this experimental study, the effect of fish n-3 fatty acids was studied on the some important enzymes of carbohydrate metabolism, hexokinase (HK), glucose-6-phosphate dehydrogenase (GOD), 6-phosphogluconate dehydrogenase (6PGD), lactate dehydrogenase (LDH), and malate dehydrogenase (MDH) in rat liver. Wistar albino rats of experimental group (n = 9) were supplemented fish omega-3 fatty acids (n-3 PUFA) as 0.4 g/kg bw. by gavage for 30 days in addition to their normal diet. Isotonic solution was given to the control group (n = 8) by the same way. At 30(th) day, the rats were killed by decapitation under ether anesthesia, autopsied and liver was removed. Spectrophotometric methods were used to determine the activities of above-mentioned enzymes in the liver.