PTPN22 gene polymorphism in Takayasus arteritis

Sahin, N.; Aksu, K.; Kamali, S.; Bicakcigil, M.; Oezbalkan, Z.; Fresko, I.; Oezer, H.; Akar, S.; Onat, A.; Cobankara, V.; Kiraz, S.; Oeztuerk, M.; Tunc, E.; Yuecel, E.; Ates, A.; Keser, G.; Inanc, M.; Direskeneli, H.; Saruhan-Direskeneli, G.

doi:10.1093/rheumatology/ken106

PTPN22 gene polymorphism in Takayasus arteritis

Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Fresko I., ...More

RHEUMATOLOGY, vol.47, no.5, pp.634-635, 2008 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 47 Issue: 5
Publication Date: 2008
Doi Number: 10.1093/rheumatology/ken106
Journal Name: RHEUMATOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.634-635
Open Archive Collection: AVESIS Open Access Collection
Süleyman Demirel University Affiliated: Yes

Abstract

Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.