PTPN22 gene polymorphism in Takayasus arteritis


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Sahin N., Aksu K., Kamali S., Bicakcigil M., Oezbalkan Z., Fresko I., ...Daha Fazla

RHEUMATOLOGY, cilt.47, ss.634-635, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 47 Konu: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1093/rheumatology/ken106
  • Dergi Adı: RHEUMATOLOGY
  • Sayfa Sayıları: ss.634-635

Özet

Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.