DNA Damages of Widely Used Pesticides; A Comet Assay Report for Chlorothalonil and Glyphosate Potassium Salt
Fresenius Environmental Bulletin, cilt.30, sa.4, ss.4170-4176, 2021 (SCI-Expanded)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 30 Sayı: 4
- Basım Tarihi: 2021
- Dergi Adı: Fresenius Environmental Bulletin
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Aerospace Database, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), CAB Abstracts, Chemical Abstracts Core, Communication Abstracts, Environment Index, Geobase, Greenfile, Metadex, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
- Sayfa Sayıları: ss.4170-4176
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
The aim of the study was to determine the gen-otoxicity of chlorothalonil and glyphosate potassium salt. Increasing use of these pesticides makes it nec-essary to determine their possible adverse effects on humans. Chlorothalonil and glyphosate potassium salt were administered in three different concentra-tions (Glyphosate potassium salt: 0.6 mg/L, 0.12 mg/L, 0.24 mg/L; Chlorothalonil: 0.03 mg/L, 0.06 mg/L, 0.15 mg/L) to human lymphocytes. An alka-line comet assay was conducted and Tail DNA Per-centage parameter was chosen to demonstrate DNA Damage. According to our results, glyphosate potas-sium salt has a considerably harmful effect on geno-toxicity. DNA damage was significantly higher in all glyphosate potassium salt groups when compared to the control group. Chlorothalonil, which is generally considered to be genotoxic, did not cause any signif-icant DNA damage.