Telomerase activity in patients with stage 2-5D chronic kidney disease

Kidir V., Aynali A., ALTUNTAŞ A., Inal S., ARIDOĞAN B., Sezer M. T.

NEFROLOGIA, vol.37, no.6, pp.592-597, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 6
  • Publication Date: 2017
  • Doi Number: 10.1016/j.nefro.2017.03.025
  • Journal Name: NEFROLOGIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.592-597
  • Keywords: Chronic kidney disease, Stage, Telomerase, BLOOD MONONUCLEAR-CELLS, CARDIOVASCULAR-DISEASE, HUMAN T, LENGTH, SENESCENCE, FAILURE, OBESITY
  • Süleyman Demirel University Affiliated: Yes

Abstract

Background: Molecular mechanisms of increased cardiovascular mortality in chronic kidney disease (CKD) associated with biological age are not well understood. Recent studies support the hypothesis that common factors responsible for this phenomenon are cellular aging and telomere dysfunction.