TURKISH JOURNAL OF MEDICAL SCIENCES, vol.45, no.5, pp.1073-1077, 2015 (SCI-Expanded)
Article / Article
TURKISH JOURNAL OF MEDICAL SCIENCES
Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
Alzheimer disease, minimal cognitive impairment, oxidative stress, isoprostane, melatonin, LIPID-PEROXIDATION, CEREBROSPINAL-FLUID, OXIDATIVE STRESS, PINEAL, BRAIN, URINE
Süleyman Demirel University Affiliated:
Background/aim: F2 alpha-isoprostane is accepted as an oxidative stress indicator and melatonin shows neuroprotective effects by antioxidative and antiamyloidogenic influences. By measuring these in patients diagnosed with minimal cognitive impairment (MCI) and Alzheimer-type dementia, we intended to demonstrate whether the measurement of these markers contributes to early diagnosis of Alzheimer disease (AD) in the MCI stage or not.