Plasma 8-isoPGF2 alpha and serum melatonin levels in patients with minimal cognitive impairment and Alzheimer disease


Sirin F. B. , Doguc D. K. , VURAL H., EREN I., Inanli I., SÜTÇÜ R., ...Daha Fazla

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.45, ss.1073-1077, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 45 Konu: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.3906/sag-1406-134
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.1073-1077

Özet

Background/aim: F2 alpha-isoprostane is accepted as an oxidative stress indicator and melatonin shows neuroprotective effects by antioxidative and antiamyloidogenic influences. By measuring these in patients diagnosed with minimal cognitive impairment (MCI) and Alzheimer-type dementia, we intended to demonstrate whether the measurement of these markers contributes to early diagnosis of Alzheimer disease (AD) in the MCI stage or not.