Disorders of Lipid Metabolism in Chronic Kidney Disease
BLOOD PURIFICATION, cilt.46, sa.2, ss.144-152, 2018 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Derleme
- Cilt numarası: 46 Sayı: 2
- Basım Tarihi: 2018
- Doi Numarası: 10.1159/000488816
- Dergi Adı: BLOOD PURIFICATION
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.144-152
- Süleyman Demirel Üniversitesi Adresli: Evet
Özet
Cardiovascular disease (CVD) is the leading cause of death in chronic kidney disease (CKD). One of the most important pathophysiological mechanisms for CVD in patients with CKD is the widespread and possibly accelerated formation of atherosclerotic plaques due to hyperlipidemia, uremic toxins, inflammation, oxidative stress, and endothelial dysfunction. Recent studies showed that the level of oxidized lowdensity lipoprotein cholesterol increases, and that high-density lipoprotein cholesterol dysfunction occurs as kidney function declines and inflammation becomes more prevalent. In this review, we aimed to discuss the effect of kidney dysfunction, oxidative stress, and inflammation on lipid profile. (C) 2018 S. Karger AG, Basel