We report the case of a 23-year-old man with Robinow syndrome (RS) and bilateral epiphora due to nasolacrimal duct obstruction associated with bilateral mucoceles. The patient underwent endoscopic dacryocystorhinostomy (DCR) on the right and endoscopic revision DCR on the left, an anterior ethmoidectomy, and a septoplasty. Subsequently, he was disease-free at his 3-month follow-up. Like patients with midface anomalies, patients with RS frequently have lacrimal system pathologies. Since early recognition of this type of midface anomaly can minimize morbidity by facilitating optimal surgical therapy, we recommend a thorough ocular evaluation of patients with RS.