Examination of Adhesion Molecules, Homocysteine and hs-CRP in Patients with Polygenic Hypercholesterolemia and Isolated Hypertriglyceridemia

Calan M., Calan O., Gonen M. S., Bilgir F., KEBAPCILAR L., Kulac E., ...More

INTERNAL MEDICINE, vol.50, no.15, pp.1529-1535, 2011 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 15
  • Publication Date: 2011
  • Doi Number: 10.2169/internalmedicine.50.4297
  • Journal Name: INTERNAL MEDICINE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1529-1535
  • Süleyman Demirel University Affiliated: Yes

Abstract

Background Increased levels of selectins, adhesion molecules, hs-CRP and homocysteine are considered important as indicators of atherosclerosis. There is a significant amount of evidence that high LDL-C levels are a risk factor for coronary artery disease, whereas the relevance of isolated triglycerides is controversial. The present study aims to compare the levels of homocysteine, hs-CRP, E-selectin, sP-selectin, VCAM-1, ICAM-1 in patients with isolated hypertriglyceridemia and polygenic hypercholesterolemia.