The hydrocarbon potentials of the carbonates and siliciclastic rocks forming the continuous Paleozoic successions in Southeast Turkey are well understood. In this study, every aspect of the sequence stratigraphy was investigated and the erosional unconformity surfaces of different origin and transgressive surfaces were defined. In this way, the Paleozoic successions of Southeast Turkey were correlated with the hydrocarbon-producing Paleozoic successions of Saudi Arabia. Based on fieldwork, new formations and members were defined and formation boundaries were slightly modified. The stratigraphic sequence extending between the Neoproterozoic igneous basement (Telbesmi Formation) and the Early Ordovician (Konur Formation) is best represented along Zabuk Valley (Derik town). Middle-Late Ordovician successions are exposed between Bedinan (Gurmese) and Yurteri villages, west of Kiziltepe town. The stratigraphic sequence between the Early Silurian (Dadas Formation) and Late Permian-Early Triassic (Gomanibrik Formation) is represented northwest of Hazro town. In these areas, many stratigraphic and sedimentologic sections were measured, and shale and sandstone samples were collected for palynological and petrographic examination to evaluate their reservoir quality. The outcrops and subsurface indicated that the thick Middle Cambrian stromatolitic algal limestone (Koruk Formation) has both source rock and reservoir rock potentials. The glaciogenic Yurteri Formation has deeply incised into the Bedinan Formation. The well-sorted and porous glaciofluvial sandstones produce oil and gas in southeast Turkey and other countries located on the Gondwana continent. The organic rich shale deposited at the base of the Silurian Dadas Formation forms a very productive source rock for the entire Paleozoic successions. Crude oil has been produced from the Late Silurian Hazro sandstone. In order to locate exploration wells in the right place, depositional environment models of all the formations, their lithofacies, isopach maps and hydrocarbon migration pathways were prepared. This is crucial for geological exploration and oil and gas production.